Rofenac 12.5 Suppositories, Mg Anti-Inflammatory And Antipyretic For Children - 10 Pcs 
                  
                
                
                                          
              
                                                    
                    Product Name
- Rofenac 12.5 mg Suppository
 
 
Scientific Name
- Diclofenac Sodium 12.5 MG SUPP
 
 
Category Of Rofenac 12.5 Mg Suppository
- Analgesic, Antipyretic & Anti-inflammatory
 
 
Mechanism Of Action Of Diclofenac
- Diclofenac which belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs) which works by
 
- Inhibits cyclooxygenase (COX)-1 and COX-2, thereby inhibiting prostaglandin synthesis
 - May also inhibit neutrophil aggregation/activation, inhibit chemotaxis, decrease proinflammatory cytokine level, and alter lymphocyte activity
 
Therapeutic Indications Of Rofenac 12.5 Mg Suppository
- relieve pain, reduce swelling and ease inflammation in conditions affecting the joints, muscles and tendons
 - Management of fever
 - treat pain and inflammation associated with dental and minor surgery
 - Inflammation of the bones and joints such as rheumatoid arthritis, osteoarthritis, acute gout and ankylosing spondylitis.
 - Back pain.
 - Sprains, strains, sports injuries, dislocations and fractures.
 - Conditions affecting the tendons such as tendonitis.
 
 
Method Of Administration Of Rofenac 12.5 Mg Suppository
- Suppositories are designed for insertion into the back passage (rectum). Never take them by mouth.
 - How to use:
 
- Lie on one side with your knees pulled up towards your chest.
 - Gently push the suppository pointed end first into your back passage (rectum) with your finger.
 - Push the suppository in as far as possible
 - Lower your legs and, if possible, stay still for a few minutes.
 - If you feel as if you need to push the suppository out, try to resist this by lying still with your buttocks pressed together.
 - It is important to keep the suppository in the rectum to allow it to melt and the medicine to be absorbed.
 - Pushing the suppository high into the rectum with your finger will help to reduce this feeling.
 - Wash your hands.
 
- Consult your physician or pharmacist if your child age between 1 – 3-year old before using
 - For children older than 1 year of age, the dose is 1-3 mg/kg/day divided into 2 or 3 doses.
 - Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
 - If you take more than you should, talk to a doctor or go to the hospital straight away.
 - If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
 - Do not take a double dose (two doses at the same time) to make up for the forgotten dose.
 
 
Undesirable Side Effects Of Rofenac 12.5 Mg Suppository
- Stomach pain, heartburn, nausea, vomiting, diarrhea, indigestion, wind, loss of appetite
 - Headache, dizziness, vertigo
 - Skin rash or spots
 - Raised levels of liver enzymes in the blood
 - Irritation where the suppository is inserted
 
 
Pregnancy & Breastfeeding Precautions While Taking Rofenac 12.5 Mg Suppository
- If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
 - Not preferred especially during the first 3 months
 
 
 
Non-Pharmacological Treatments & Advice To Reduce Pain
- A lot of people find relief from gentle massage, and some hospice agencies have volunteers who are trained in massage therapy.
 - Relaxation techniques.
 - Physical therapy
 - Pet therapy
 - Gel packs.
 
 
 
Warnings & Special Precautions While Taking Rofenac 12.5 Mg Suppository
- Suppositories may also occasionally cause itching or burning in your back passage.
 - Stop taking the medication and tell your doctor straight away if you notice:
 
- Sudden and crushing chest pain (signs of myocardial infarction or heart attack)
 - Breathlessness, difficulty breathing when lying down, swelling of the feet or legs (signs of heart failure)
 - Sudden weakness or numbness in the face, arm or leg especially on one side of the body.
 - sudden loss or disturbance of vision; sudden difficulty in speaking or ability to understand speech; sudden migraine-like headaches which happen for the first time, with or without disturbed vision. These symptoms can be an early sign of a stroke.
 - Stomach pain, indigestion, heartburn, wind, nausea (feeling sick) or vomiting (being sick)
 - Any sign of bleeding in the stomach or intestine, for example, when emptying your bowels,
 - blood in vomit or black, tarry feces
 - Allergic reactions can include skin rash, itching, bruising, painful red areas, peeling or blistering
 
- Tell your doctor or pharmacist if you are taking any of the following:
 
- Medicines to treat diabetes
 - Anticoagulants (blood-thinning tablets like warfarin)
 - Diuretics (water tablets)
 - Lithium (used to treat some mental problems)
 - Methotrexate (for some inflammatory diseases and some cancers)
 - Ciclosporin and tacrolimus (used to treat some inflammatory diseases and after transplants)
 - Trimethoprim (a medicine used to prevent or treat urinary tract infections)
 - Quinolone antibiotics (for infections)
 - Any other NSAID or COX-2 (cyclo-oxygenase-2) inhibitor, for example, aspirin or ibuprofen
 - Cardiac glycosides (for example digoxin), used to treat heart problems
 - Medicines known as SSRIs used to treat depression
 - Oral steroids (an anti-inflammatory drug)
 - Medicines used to treat heart conditions or high blood pressure, for example beta blockers or ACE inhibitors
 - Voriconazole (a medicine used to treat fungal infections)
 - Phenytoin (a medicine used to treat seizures)
 - Colestipol/cholestyramine (used to lower cholesterol)
 
 
Storage Conditions Of Rofenac 12.5 Mg Suppository
- store below 25°c
 - Keep this medicine out of the sight and reach of children.
 - Store in the original package to protect from moisture.
 - Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.
 
 
For More Information About Diclofenac